This webinar introduces the CALM Study(Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability), a single-site, open-label clinical trial currently enrolling at Beth Israel Deaconess Medical Center (Boston, MA) to evaluate the feasibility and safety of non-invasive treatment with the MyoRegulator device in individuals with ALS. The MyoRegulator device is an investigational neuromodulation device developed by PathMaker Neurosystems Inc. that utilizes non-invasive multi-site direct current stimulation (DCS). Thepresentation will provide an overview of PathMaker’s multi-site DCS technology, pre-clinical findings in ALS models and early clinical experience, and will provide attendees with information about the CALM study design and eligibility criteria.