On 16 May 2014, a news story appeared on American television and online, highlighting dramatic improvements in a patient with ALS taking a nutritional supplement called lunasin. This webinar will review how ALSUntangled investigated this story and eventually graded lunasin with regard to its table of evidence system. It will show how lunasin was then incorporated into a patient-centric pilot trial within the "replication of ALS reversals" program. The final results of this pilot trial will be presented. Finally, it will review other theories that might explain ALS reversals, show preliminary results from experiments testing these theories, and describe our next steps.