In this webinar Richard Bedlack, MD, PhD, Duke ALS Clinic, reviews alternative and off-label treatments for ALS. He demonstrates the huge number of these, the reasons patients try them, and some of the risks involved. He also explains an international program called ALSUntangled which uses social networking tools to help patients and families critically review alternative and off-label treatments and highlight some of the lessons learned in this program over the past 7 years.