A Clinical Trial of Creatine in ALS

Study Purpose:

Mitochondrial dysfunction occurs early in the course of ALS, and the mitochondria may be an important site for therapeutic intervention. Creatine stabilizes the mitochondrial transition pore, and is important in mitochondrial ATP production. In a transgenic mouse model of ALS, administration of creatine prolongs survival and preserves motor function and motor neurons.

Study Status:

Not recruiting

Disease:

Amyotrophic Lateral Sclerosis (ALS) , Familial ALS , Sporadic ALS

Study Type:

Interventional

Type of Intervention:

Drug Trial

Intervention Name:

Placebo:

Phase:

N/A

Study Chair(s)/Principal Investigator(s):

Jeremy Shefner (SUNY)

Clinicaltrials.gov ID:

Neals Affiliated?

Yes

Coordinating Center Contact Information