Control Cohort CTRL COH

Study Purpose:

Autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS) are rare disease that could be difficult to diagnose. So it necessary to obtain numerous sample from different disease to develop more specific diagnosis kit It could be possible through the characterisation of new genetic biomarkers.

Study Status:

Not yet recruiting


Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis

Study Type:


Type of Intervention:


Intervention Name:

Collection of biological sample (blood and/or CSF)





Study Chair(s)/Principal Investigator(s):

Jerome Honnorat, Pr, Centre de référence des syndromes neurologiques paranéoplasiques et encéphalites auto-immunes, Lyon, France ID:


Neals Affiliated?


Coordinating Center Contact Information

Jerome Honnorat, Pr / email hidden; JavaScript is required / (33) 4 72 35 78 06

Study Sponsor:

Hospices Civils de Lyon

Estimated Enrollment:


Estimated Study Start Date:

09 / 16 / 2022

Estimated Study Completion Date:

09 / 16 / 2027

Posting Last Modified Date:

09 / 14 / 2022

Date Study Added to

05 / 11 / 2022

Minimum Age:

18 Years

Maximum Age:


Inclusion Criteria:

- patient with consent

- patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.

Exclusion Criteria:

- refusal consent

- patient with neurological disorder compatible with paraneoplastic neurological syndrome or auto-immune encephalitis

- patient under guardianship

Hospices Civils de Lyon

Jerome HONNORAT, Pr / (33) 4 72 35 78 06 / email hidden; JavaScript is required

Principal Investigator : Jerome HONNORAT

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