Study Purpose:
200 cases of ALS patients were collected to explore whether sleep disorders are related to earlier onset age, and whether sleep disorders accelerate the progress of ALS and shorten the survival time of ALS patients.Study Status:
Recruiting
Disease:
Amyotrophic Lateral Sclerosis
Study Type:
Observational
Type of Intervention:
N/A
Intervention Name:
N/A
Placebo:
N/A
Phase:
N/A
Study Chair(s)/Principal Investigator(s):
Dongsheng Fan, Peking University Third Hospital
Clinicaltrials.gov ID:
Neals Affiliated?
No
Coordinating Center Contact Information
Dongsheng Fan / email hidden; JavaScript is required / +86 13701023871
Full Study Summary:
200 patients with ALS were collected. 1) sleep disorders were assessed by Pittsburgh sleep quality index (PSQI) and Epworth Sleepiness Scale (epworth) at baseline Sleeping Scale，ESS）； 2) Name, age, gender and onset site were collected to explore whether sleep disorders were associated with earlier onset age; 3) The patients' function (ALSFRS-R) at baseline and every 3 months within 2 years were collected, and the end-point time (death and invasive breathing) was recorded to evaluate whether sleep disturbance accelerated the decline of patients' function and shortened their short-term survival.
Study Sponsor:
Peking University Third Hospital
Estimated Enrollment:
200
Estimated Study Start Date:
08 / 01 / 2020
Estimated Study Completion Date:
03 / 31 / 2022
Posting Last Modified Date:
07 / 07 / 2021
Date Study Added to neals.org:
07 / 07 / 2021
Minimum Age:
N/A
Maximum Age:
N/A
Inclusion Criteria:- Patients who have been diagnosed in the Department of Neurology of the Third Hospital of Beijing Medical University since August 2020. The clinical diagnosis of patients with amyotrophic lateral sclerosis includes: probable and define;
- Informed consent has been signed.
Exclusion Criteria:
- Those who can not cooperate to complete the scale and receive follow-up.
Peking University Third Hospital | Recruiting
Dongsheng Fan
Beijing, Beijing
100098
China