Study Purpose:
Using the original MRI images of 16 ALS patients and 16 normal controls matched by gender, age and education level in the previous study, the differences of brain volume in different parts of ALS patients and normal controls, and the correlation between brain structure and clinical characteristics were compared by precise brain volume quantitative analysis technology.Study Status:
Not recruiting
Disease:
Amyotrophic Lateral Sclerosis
Study Type:
Observational
Type of Intervention:
N/A
Intervention Name:
N/A
Placebo:
N/A
Phase:
N/A
Study Chair(s)/Principal Investigator(s):
Shan Ye, Peking University Third Hospital
Clinicaltrials.gov ID:
Neals Affiliated?
No
Coordinating Center Contact Information
Full Study Summary:
This study was a retrospective study. The subjects were 16 ALS patients and 16 normal controls. Previous studies have collected patients' age, gender and education level; The onset site, onset time, bulbar involvement, diagnostic grade, ALSFRS-R score, application of ventilator, application of lirutai, gastrostomy; Age, gender and education level were collected in the control group. Accurate quantitative analysis of brain volume was performed on the original brain MRI images of the two groups.
Study Sponsor:
Peking University Third Hospital
Estimated Enrollment:
32
Estimated Study Start Date:
01 / 01 / 2015
Estimated Study Completion Date:
01 / 31 / 2021
Posting Last Modified Date:
07 / 07 / 2021
Date Study Added to neals.org:
07 / 07 / 2021
Minimum Age:
N/A
Maximum Age:
N/A
Inclusion Criteria:- Diagnosed ALS patients
- healthy volunteers
Exclusion Criteria:
- none
Peking University Third Hospital
Beijing, Beijing
100000
China