Phenotype, Genotype and Biomarkers 2

Study Purpose:

The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), progressive muscular atrophy (PMA) and multisystem proteinopathy (MSP). More precisely, the investigator wants to identify the links that exist between the disease phenotype (phenotype refers to observable signs and symptoms) and the disease genotype (genotype refers to your genetic information). The investigator also wants to identify biomarkers of ALS and related diseases.

Study Status:

Recruiting

Disease:

Amyotrophic Lateral Sclerosis (ALS) , Familial ALS , Sporadic ALS , Primary Lateral Sclerosis (PLS) , Hereditary Spastic Paraplegia (HSP) , Healthy Volunteer , Healthy Volunteer with a Family History of ALS

Study Type:

Observational

Type of Intervention:

N/A

Intervention Name:

N/A

Placebo:

N/A

Phase:

N/A

Study Chair(s)/Principal Investigator(s):

Michael Benatar, MD, PhD University of Miami

Clinicaltrials.gov ID:

NCT04875416

Neals Affiliated?

No

Coordinating Center Contact Information

Study Sponsor:

University of Miami

Estimated Enrollment:

300

Estimated Study Start Date:

01 / 08 / 2021

Estimated Study Completion Date:

06 / 30 / 2024

Posting Last Modified Date:

05 / 12 / 2021

Date Study Added to neals.org:

05 / 12 / 2021