Registration Study of Natural History and Clinical Characteristics of Amyotrophic Lateral Sclerosis (ALS) in Mainland China

Study Purpose:

A multi-center registration study of natural history and clinical characteristics of ALS in mainland China

Study Status:

Not recruiting


Amyotrophic Lateral Sclerosis

Study Type:

Observational [Patient Registry]

Type of Intervention:


Intervention Name:






Study Chair(s)/Principal Investigator(s):

Dongsheng Fan, MD, PhD, Peking University Third Hospital ID:


Neals Affiliated?


Coordinating Center Contact Information

Dongsheng Fan, MD, PhD / email hidden; JavaScript is required / +86-15611908107

Full Study Summary:

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease of unknown etiology that is currently incurable. This study is a national multi-center registration study. The study collects general information of ALS patients including medical history, disease characteristics, clinical treatment data, and patient information for different visits in different centers. The aim of the study is: a) describe the distribution of ALS in mainland China(explore the differences in the number of ALS at different times, different regions, and different populations) and further find the reasons that affect the distribution of ALS, b) study the development of ALS in mainland China and the corresponding changes in the characteristics of the disease, c) explore factors that influence the prognosis of ALS.

Study Sponsor:

Peking University Third Hospital

Estimated Enrollment:


Estimated Study Start Date:

03 / 20 / 2020

Estimated Study Completion Date:

03 / 20 / 2023

Posting Last Modified Date:

04 / 28 / 2020

Date Study Added to

03 / 31 / 2020

Minimum Age:

18 Years

Maximum Age:

80 Years

Inclusion Criteria:

- Clinical diagnosis of laboratory-supported probable, probable, or definite ALS according to EI Escorial diagnostic criteria

- Age: 18-70 years

Exclusion Criteria:

- Refuse to cooperate or reject the informed consent

Peking University Third Hospital | Recruiting

Dongsheng Fan / +861082265032 / email hidden; JavaScript is required

Beijing, Beijing 100191