Study Purpose:
it will be conducted a randomized parallel controlled trial with patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) to compare two techniques to lung recruitment and cough augmentation, to assess their effects on pulmonary function, global functionally, swallowing and ability to speech in these population.Study Status:
Not recruiting
Disease:
Amyotrophic Lateral Sclerosis , Neuromuscular Diseases
Study Type:
Interventional
Type of Intervention:
Device
Intervention Name:
Breath Stacking Group, Breath stacking and EMT
Placebo:
Phase:
N/A
Study Chair(s)/Principal Investigator(s):
Vinicius Maldaner, Hospital de Apoio de Brasilia
Clinicaltrials.gov ID:
Neals Affiliated?
No
Coordinating Center Contact Information
Full Study Summary:
age over 18 years preserved cognition, evidenced by a score greater than or equal to 24 points in the Mini-Mental Status Exam; no barium allergies; without tracheostomy or invasive mechanical ventilation; no diaphragmatic pacemaker and without associated respiratory disease.Participants are excluded if they have pregnancy; previous kidney disease or other concomitant diseases; respiratory diseases and hospitalization in intensive care units (ICUs) during the study.
Study Sponsor:
Escola Superior de Ciencias da Saude
Estimated Enrollment:
50
Estimated Study Start Date:
01 / 06 / 2020
Estimated Study Completion Date:
12 / 01 / 2022
Posting Last Modified Date:
04 / 04 / 2023
Date Study Added to neals.org:
01 / 13 / 2020
Minimum Age:
18 Years
Maximum Age:
N/A
Inclusion Criteria:- diagnosis of neuromuscular disease confirmed by neurologists at the referral center for neuromuscular diseases at Brasília prior to screening for recruitment
- age over 18 years
- preserved cognition, evidenced by a score greater than or equal to 24 points in the Mini-Mental Status Exam;
- no barium allergies
- without tracheostomy or invasive mechanical ventilation
- no diaphragmatic pacemaker
- without associated respiratory disease
Exclusion Criteria:
- pregnancy
- previous kidney disease or other concomitant diseases .respiratory diseases and hospitalization in intensive care units (ICUs) during the study.
Hospital de Apoio de Brasilia
Brasilia, DF
700000
Brazil