Evaluation and Characterization of Infraclinical Sensory Deficits in Amyotrophic Lateral Sclerosis by Brain Imaging and Electrophysiology

Study Purpose:

The main objective is to determine the origin of somatosensory alteration in patients with ALS and to evaluate its impact on brain activity by coupling different imaging modalities and indirect electrophysiology.

The secondary objective is to evaluate whether the observed functional changes in MEG / EEG and functional MRI correlate with structural lesions revealed with diffusion MRI (anatomo-functional connectivity of the brain).

Study Status:

Not recruiting

Disease:

Amyotrophic Lateral Sclerosis

Study Type:

Interventional

Type of Intervention:

Device

Intervention Name:

functional MRI, structural MRI, EEG/MEG

Placebo:

No

Phase:

N/A

Study Chair(s)/Principal Investigator(s):

Pierre-Francois Pradat, MD, PhD, Assistance Publique - Hôpitaux de Paris, Veronique Marchand-Pauvert, PhD, Institut National de la Santé Et de la Recherche Médicale, France

Clinicaltrials.gov ID:

NCT03694132

Neals Affiliated?

No

Coordinating Center Contact Information

Study Sponsor:

Institut National de la Santé Et de la Recherche Médicale, France

Estimated Enrollment:

52

Estimated Study Start Date:

11 / 26 / 2018

Estimated Study Completion Date:

04 / 06 / 2022

Posting Last Modified Date:

12 / 21 / 2018

Date Study Added to neals.org:

10 / 03 / 2018