Study Purpose:This is a prospective investigation of the effects of Laughter therapy (LT) on perceived stress, self-efficacy, mood and other wellness measures in people with the following neurological conditions: Alzheimer's disease, amyotrophic lateral sclerosis, brain injury, Huntington's Disease, multiple sclerosis, Parkinson's Disease, post-stroke, spinal cord injury.
Alzheimer's Disease , Amyotrophic Lateral Sclerosis , Brain Injury , Huntington's Disease , Multiple Sclerosis , Parkinson's Disease , Stroke , Spinal Cord Injury
Type of Intervention:
Study Chair(s)/Principal Investigator(s):
Theodore R Brown, MD, MPH, Evergreen Healthcare
Coordinating Center Contact Information
Kirkland, Washington, 98034 United States
Full Study Summary:
Brown, Theodore R., M.D., MPH
Estimated Study Start Date:
07 / 01 / 2016
Estimated Study Completion Date:
08 / 01 / 2018
Posting Last Modified Date:
09 / 26 / 2018
Date Study Added to neals.org:
04 / 26 / 2016
- Diagnosis based on medical record review of one of the following neurological diseases: Alzheimer's disease, amyotrophic lateral sclerosis, brain injury, Huntington's Disease, Multiple Sclerosis, Parkinson's Disease, Post-Stroke, Spinal Cord Injury.
- Medically stable for at least 2 months.
- Not participating in Laughter therapy for 30 days prior to screening.
- Females who are pregnant
- Any unstable medical condition
- Severe cognitive deficits that would interfere with participation (e.g. unable to follow commands).
- Severe abdominal pain, chest pain or back pain.
- Abdominal, chest or back surgery within 90 days.
- Psychosis or severe mental illness.
- Untreated hernia.
- Persistent cough.
- Advanced hemorrhoids.
- Uncontrolled Hypertension - SBP >170 or DBP >105.