Study Purpose:
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine if a disease is responding to therapy or progressing.Study Status:
Not recruiting
Disease:
Amyotrophic Lateral Sclerosis , Muscular Dystrophy , Radiculopathy , Myopathy , Polyneuropathy and Mononeuropathies , Trauma Injury , Orthopedic Disorder
Study Type:
Observational
Type of Intervention:
N/A
Intervention Name:
N/A
Placebo:
N/A
Phase:
N/A
Study Chair(s)/Principal Investigator(s):
N/A
Clinicaltrials.gov ID:
Neals Affiliated?
No
Coordinating Center Contact Information
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215 United States
Full Study Summary:
Primary Outcome Measures:
-Quantitative ultrasound data, including quantified grayscale data and backscattered acoustic data [ Time Frame: 1 year ] [ Designated as safety issue: No ]
-Ultrasound data will be collected on multiple muscles in each person. The images will then be quantified using either 1. A grayscale technique in which the images themselves are analyzed via standard image software (e.g., Adobe Photoshop) as to level of echo intensity in a pre-specific region of interest or 2. the raw quantified backscatter data is captured by the transducer, expressed as a unit of power, in the same pre-specified area of interest
Study Sponsor:
Beth Israel Deaconess Medical Center
Estimated Enrollment:
223
Estimated Study Start Date:
12 / 01 / 2013
Estimated Study Completion Date:
03 / 01 / 2020
Posting Last Modified Date:
03 / 11 / 2022
Date Study Added to neals.org:
04 / 07 / 2014
Minimum Age:
18 Years
Maximum Age:
90 Years
Inclusion Criteria:- History of a well-defined, localized or generalized neuromuscular condition producing weakness or muscle atrophy, including disuse atrophy.
Exclusion Criteria:
- Multiple generalized neuromuscular conditions.
Beth Israel Deaconess Medical Center
Boston, Massachusetts
02215
United States