Study Purpose:
Amyotrophic Lateral Sclerosis (ALS) is a progressive fatal neurodegenerative disease affecting motor neurons. Early diagnosis is essential for the success of clinical trials and objective biomarkers are needed for monitoring disease progression. Nerve and muscle ultrasound may provide this information.This study will collect pilot data to evaluate the value of muscle and nerve ultrasound to identify and monitor disease progression in ALS.
Study Status:
Not recruiting
Disease:
ALS
Study Type:
Observational
Type of Intervention:
N/A
Intervention Name:
N/A
Placebo:
N/A
Phase:
N/A
Study Chair(s)/Principal Investigator(s):
N/A
Clinicaltrials.gov ID:
Neals Affiliated?
No
Coordinating Center Contact Information
Duke University Medical Center
Durham, North Carolina, 27710 United States
Full Study Summary:
Amyotrophic Lateral Sclerosis (ALS) is a progressive fatal neurodegenerative disease affecting motor neurons. Early diagnosis is essential for the success of clinical trials and objective biomarkers are needed for monitoring disease progression. Nerve and muscle ultrasound may provide this information.
All participants will receive nerve and muscle ultrasound. Ultrasound of 6 muscles and 2 nerves will be performed.
All participants will receive nerve and muscle ultrasound. Ultrasound of 6 muscles and 2 nerves will be performed.
Study Sponsor:
Duke University
Participant Duration:
1 year
Estimated Enrollment:
40
Estimated Study Start Date:
01 / 31 / 2013
Estimated Study Completion Date:
03 / 01 / 2015
Posting Last Modified Date:
03 / 11 / 2015
Date Study Added to neals.org:
02 / 07 / 2013
Minimum Age:
18 Years
Maximum Age:
N/A
Inclusion Criteria:- Subjects referred to the electromyography laboratory for ALS.
Exclusion Criteria:
- Patients with known comorbid myopathy or neuropathy will be excluded from the study.
- Patients unable to provide their own consent will be excluded.
Duke University Medical Center
Durham, North Carolina
27710
United States