Study Purpose:The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.
Tetraplegia , Spinal Cord Injuries , Amyotrophic Lateral Sclerosis , Brain Stem Infarctions , Locked in Syndrome , Muscular Dystrophy
Type of Intervention:
Placement of the BrainGate2 sensor(s) into the motor-related cortex
Study Chair(s)/Principal Investigator(s):
Leigh R Hochberg, M.D., Ph.D., Massachusetts General Hospital
Coordinating Center Contact Information
Massachusetts General Hospital
Boston, Massachusetts, 02114 United States
Full Study Summary:
Leigh R. Hochberg, MD, PhD.
approximately 13 months
Estimated Study Start Date:
05 / 01 / 2009
Estimated Study Completion Date:
12 / 01 / 2038
Posting Last Modified Date:
09 / 21 / 2022
Date Study Added to neals.org:
06 / 03 / 2009
This study is invasive and requires surgery. You must live within 3 hours of Boston, Massachusetts, Providence, RI, Palo Alto, California or Cleveland, Ohio to participate.
Can participants use Riluzole?
- Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis or other motor neuron disorders
- Complete or incomplete tetraplegia (quadriplegia)
- Must live within a three-hour drive of the Study site
- (There are additional inclusion criteria)
- Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses
- Chronic oral or intravenous steroids or immunosuppressive therapy
- Other serious disease or disorder that could seriously affect ability to participate in the study
- (There are additional exclusion criteria)
University of California, Davis | Recruiting
Principal Investigator : David M Brandman, MD, PhD
Stanford University School of Medicine | Recruiting
Principal Investigator : Jaimie Henderson, M.D.
Emory University School of Medicine | Recruiting
Principal Investigator : Nicholas Au Yong, M.D., Ph.D.
Massachusetts General Hospital | Recruiting
Sub-Investigator : Ziv Williams, M.D., Ph.D.
Providence VA Medical Center | Recruiting
Sub-Investigator : Leigh R Hochberg, M.D., Ph.D.
Providence, Rhode Island